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[Other names] Astragali Radix Extract; Astragalus Propinquus Extract; Astragalus Root Extract; Astragalus Membranaceus Extract
[ Specification ] 20%Astragaloside ,50%Polysaccharide
[ Detection method ] UV
[ Botanical Name ] Astragalus Membranaceus(Fisch) Bunge
[ Appearance ] Brown powder
[ Application ] Pharmaceutical field, health care product field.
Astragalus Extract is derived from the root of Astragalus Membranaceus in the pea family.The portion of the plant used medicinally is the fourth seven-year-old dried root collected in the spring and autumn.Astragalus Extract is used by practitioners of Traditional Chinese Medicine strengthen or tone the body’s overall vitality.
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Astragalus membranaceus (Fisch.) Bunge repairs intestinal mucosal injury induced by LPS in mice – PubMed
Astragalus membranaceus (Fisch.) Bunge repairs intestinal mucosal injury induced by LPS in mice
BMC Complement Altern Med. 2018; 18: 230.
Astragalus membranaceus (Fisch.) Bunge is one of the most widely used traditional Chinese herbal medicines. It is used as immune stimulant, tonic, antioxidant, hepatoprotectant, diuretic, antidiabetic, anticancer, and expectorant. The purpose of the study was to investigate the curative effects of the decoction obtained from Astragalus membranaceus root in intestinal mucosal injury induced by LPS in mice. An LPS-induced intestinal mucosal injury mice model was applied in the study.
The mice were post-treated with Astragalus membranaceus decoction (AMD) for 4 days after 3 days LPS induction. ELISA kit was used to detect the content of tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-4,IL-6 and IL-8 in the serum of each group mice. The morphological changes in intestinal mucosa at the end of the experiments were observed. Both VH (villus height) and CD (crypt depth) were measured using H&E-stained sections.
There were significant differences in IL-1β, IL-4,IL-6, IL-8 and TNF-α levels in AMD-treated group on the 7th day compared to the controls group. The VH was lower in duodenum, jejunum and the ileum in LPS-treated mice compared to the control animals. Similarly, there was also decrease in V/C. Compared to the control mice, for AMD-treated mice, VH and CD had no significantly differences.
Astragalus membranaceus reduced intestinal mucosal damage and promoted tissue repair by inhibiting the expression of inflammatory cytokine.
Keywords: Astragalus membranaceus (Fisch.) Bunge, Decoction, Mice, Lipopolysaccharide
Intestinal mucosa is a natural barrier against bacteria. It prevents viruses and other harmful bacteria from entering the blood . Endotoxin is the lipopolysaccharide (LPS) in the cell wall of Gram-negative bacteria, which has a variety of biological activity and is decomposed and released in the process of ba…
Astragalus membranaceus Fisch. ex Bunge
- GBIF Backbone Taxonomy
- Published in
- Mém. Acad. Imp. Sci. Saint Pétersbourg, Sér. 7, 11(16): 25 (1868)
Astragalus membranaceus (Fisch.) Bunge
Tên tiếng Việt: Hoàng kỳ, Co nấm mò (Thái)
Tên khoa học: Astragalus propinquus Schischkin – Astragalus membranaceus (Fisch.) Bunge
Họ thực vật: Fabaceae
Công dụng: Chữa sốt, đái đường, đái đục, lở loét, phong thấp, suy nhược cơ thể, lở loét mãn tính (Rễ).
Phân bố: Lào Cai. Cây nhập trồng.
Astragalus membranaceus Fisch. ex Bunge | Plants of the World Online | Kew Science
Astragalus membranaceus Fisch. ex Bunge appears in other Kew resources:
First published in Mém. Acad. Imp. Sci. Saint Pétersbourg, Sér. 7, 11(16): 25 (1868)
Not accepted by
- Govaerts, R. (1995). World Checklist of Seed Plants 1(1, 2): 1-483, 529. MIM, Deurne. [Cited as Astragalus propinquus.]
- Podlech, D & Zarre, S. (2013). A taxonomic revision of the genus Astragalus L. (Leguminosae) in the Old World 1: 1-822. Naturhistorisches Museum Wien. [Cited as Astragalus mongholicus.]
The International Plant Names Index and World Checklist of Selected Plant Families 2022. Published on the Internet at //apps.kew.org/wcsp/
© Copyright 2017 International Plant Names Index and World Checklist of Selected Plant Families. /licenses/by/3.0
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Astragalus Extract, Astragali Radix Extract, Astragalus Membranaceus, Astragalus Extract Sales, Bulk Buy Astragalus Extract, Herbal Extracts, Astragalus Membranaceus Suppliers, Strengthen or tone the body’s overall vitality